Gonadotropin chorionic
Gonadotropin, chorionic is a protein pharmaceutical. It is currently being investigated in clinical studies. It is known to target lutropin-choriogonadotropic hormone receptor.
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2Y
5Y
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
Chorionic gonadotropin, Novarel (discontinued: A.p.l, Chorionic gonadotropin, Novarel)
Drug Products
FDA
EMA
Reference product - 351(a)
Reference product - 351(a)
Interchangeable product - 351(k)
Interchangeable product - 351(k)
Biosimilar product - 351(k)
Biosimilar product - 351(k)
Chorionic gonadotropin
Tradename | Proper name | Company | Number | Date | Products |
|---|---|---|---|---|---|
| Novarel | chorionic gonadotropin | Ferring Pharmaceuticals | N-17016 RX | 1974-01-15 | 1 products |
| Chorionic Gonadotropin | chorionic gonadotropin | Fresenius Kabi | N-17067 RX | 1973-03-05 | 1 products |
Show 4 discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| chorionic gonadotropin | Biologic Licensing Application | 2020-04-02 |
| novarel | Biologic Licensing Application | 2024-11-19 |
| pregnyl | Biologic Licensing Application | 2024-12-24 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| female infertility | EFO_0008560 | D007247 | N97 |
| hypogonadism | HP_0000044 | D007006 | E23.0 |
| cryptorchidism | EFO_0004562 | D003456 | Q53.1 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
589 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infertility | D007246 | HP_0000789 | — | — | — | — | 1 | 3 | 4 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | — | 1 | 1 | — | 2 |
| Ovarian hyperstimulation syndrome | D016471 | — | — | — | — | — | 2 | — | 2 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Assisted reproductive techniques | D027724 | — | — | — | — | 1 | — | — | 1 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | — | 1 | — | — | 1 |
| Body weight | D001835 | EFO_0004338 | — | — | — | 1 | — | — | 1 |
| Hiv | D006678 | — | — | — | — | 1 | — | — | 1 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | — | — | 1 | — | — | 1 |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | — | — | 1 | — | — | 1 |
| Body weight changes | D001836 | — | — | — | — | 1 | — | — | 1 |
| Fasting | D005215 | EFO_0002756 | — | — | — | 1 | — | — | 1 |
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Polycystic ovary syndrome | D011085 | EFO_0000660 | E28.2 | — | — | — | — | 1 | 1 |
| Syndrome | D013577 | — | — | — | — | — | — | 1 | 1 |
| Melanoma | D008545 | — | — | — | — | — | — | 1 | 1 |
| Ovulation induction | D010062 | — | — | — | — | — | — | 1 | 1 |
| Telomere | D016615 | EFO_0004359 | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Gonadotropin chorionic |
| INN | — |
| Description | Choriogonadotropin beta chain [Precursor]; Glycoprotein hormones alpha chain [Precursor]; |
| Classification | Protein |
| Drug class | atropine derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201509 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
Target
Agency Approved
No data
Alternate
LHCGR
LHCGR
Organism
Homo sapiens
Gene name
LHCGR
Gene synonyms
LCGR, LGR2, LHRHR
NCBI Gene ID
Protein name
lutropin-choriogonadotropic hormone receptor
Protein synonyms
hypergonadotropic hypogonadism, LHR, LSH-R, Luteinizing hormone receptor, lutropin/choriogonadotropin receptor
Uniprot ID
Mouse ortholog
Lhcgr (16867)
lutropin-choriogonadotropic hormone receptor (P30730)
Variants
No data
Financial
No data
Trends
PubMed Central
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2,242 adverse events reported
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