Gonadotropin chorionic
Gonadotropin, chorionic is a protein pharmaceutical. It is currently being investigated in clinical studies. It is known to target lutropin-choriogonadotropic hormone receptor.
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Commercial
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Clinical
Clinical Trials
1043 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infertility | D007246 | EFO_0000545 | — | 26 | 44 | 68 | 114 | 185 | 417 |
| Female infertility | D007247 | EFO_0008560 | N97 | 14 | 10 | 8 | 16 | 47 | 89 |
| Polycystic ovary syndrome | D011085 | EFO_0000660 | E28.2 | 11 | 6 | 13 | 11 | 22 | 58 |
| Syndrome | D013577 | — | — | 5 | 4 | 4 | 9 | 25 | 45 |
| Fertilization in vitro | D005307 | — | — | 1 | 4 | 7 | 15 | 19 | 45 |
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | 1 | 2 | 3 | 4 | 24 | 33 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 3 | 17 | 6 | 1 | 4 | 31 |
| Ovulation induction | D010062 | — | — | 3 | 6 | 4 | 4 | 12 | 29 |
| Ovarian hyperstimulation syndrome | D016471 | — | — | 1 | 3 | 2 | 10 | 8 | 24 |
| Hypogonadism | D007006 | — | E23.0 | 2 | 3 | 4 | 7 | 8 | 24 |
Show 52 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 2 | 5 | 2 | — | 3 | 10 |
| Gestational trophoblastic disease | D031901 | — | O01.9 | 1 | 3 | 4 | — | 4 | 10 |
| Helping behavior | D006379 | — | — | — | 1 | 6 | — | 1 | 8 |
| Trophoblastic neoplasms | D014328 | — | — | — | 1 | 4 | — | 4 | 8 |
| Infections | D007239 | EFO_0000544 | — | 2 | 5 | 1 | — | 1 | 7 |
| Induced abortion | D000028 | — | — | — | — | 1 | — | 6 | 7 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 2 | 1 | — | 3 | 6 |
| Communicable diseases | D003141 | — | — | 1 | 4 | 1 | — | — | 5 |
| Covid-19 | D000086382 | — | U07.1 | 1 | 3 | 1 | — | — | 5 |
| Pre-eclampsia | D011225 | EFO_0000668 | O14 | — | — | 1 | — | 3 | 4 |
Show 26 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple myeloma | D009101 | — | C90.0 | 2 | 3 | — | — | 1 | 5 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | 4 | — | — | 1 | 5 |
| Premature menopause | D008594 | — | E28.31 | 3 | 1 | — | — | 1 | 4 |
| Graft vs host disease | D006086 | — | D89.81 | 3 | 3 | — | — | — | 4 |
| Urinary bladder neoplasms | D001749 | — | C67 | 2 | 1 | — | — | 1 | 4 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 2 | 2 | — | — | — | 4 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 1 | 2 | — | — | 2 | 4 |
| Plasma cell neoplasms | D054219 | — | — | 1 | 1 | — | — | 1 | 3 |
| Leiomyoma | D007889 | — | D25 | 1 | 1 | — | — | 2 | 3 |
| Adenocarcinoma | D000230 | — | — | — | 3 | — | — | — | 3 |
Show 61 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Premature birth | D047928 | EFO_0003917 | O60 | 2 | — | — | — | 3 | 5 |
| Wounds and injuries | D014947 | — | T14.8 | 1 | — | — | — | 3 | 4 |
| Disease | D004194 | EFO_0000408 | R69 | 1 | — | — | — | 2 | 3 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 2 | — | — | — | 1 | 3 |
| Fibrosis | D005355 | — | — | 1 | — | — | — | 1 | 2 |
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | 1 | — | — | — | 1 | 2 |
| Spondylarthritis | D025241 | — | — | 1 | — | — | — | 1 | 2 |
| Spondylitis | D013166 | — | M46.9 | 1 | — | — | — | 1 | 2 |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | 1 | — | — | — | 1 | 2 |
| Non-alcoholic fatty liver disease | D065626 | EFO_0003095 | K75.81 | 1 | — | — | — | 1 | 2 |
Show 28 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pregnancy tests | D011258 | — | — | — | — | — | — | 6 | 6 |
| Down syndrome | D004314 | EFO_0001064 | Q90 | — | — | — | — | 4 | 4 |
| Asthma | D001249 | EFO_0000270 | J45 | — | — | — | — | 4 | 4 |
| Corpus luteum maintenance | D003340 | — | — | — | — | — | — | 3 | 3 |
| Unplanned pregnancy | D049168 | — | — | — | — | — | — | 3 | 3 |
| Alzheimer disease | D000544 | EFO_0000249 | F03 | — | — | — | — | 3 | 3 |
| Inflammation | D007249 | MP_0001845 | — | — | — | — | — | 3 | 3 |
| Liver diseases | D008107 | EFO_0001421 | K70-K77 | — | — | — | — | 3 | 3 |
| Melanoma | D008545 | — | — | — | — | — | — | 2 | 2 |
| Fertility preservation | D059247 | — | — | — | — | — | — | 2 | 2 |
Show 165 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Gonadotropin chorionic |
| INN | — |
| Description | Choriogonadotropin beta chain [Precursor]; Glycoprotein hormones alpha chain [Precursor]; |
| Classification | Protein |
| Drug class | atropine derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201509 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
Target
Agency Approved
No data
Alternate
LHCGR
LHCGR
Organism
Homo sapiens
Gene name
LHCGR
Gene synonyms
LCGR, LGR2, LHRHR
NCBI Gene ID
Protein name
lutropin-choriogonadotropic hormone receptor
Protein synonyms
hypergonadotropic hypogonadism, LHR, LSH-R, Luteinizing hormone receptor, lutropin/choriogonadotropin receptor
Uniprot ID
Mouse ortholog
Lhcgr (16867)
lutropin-choriogonadotropic hormone receptor (P30730)
Variants
No data
Financial
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2,189 adverse events reported
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